Chronic Wounds & Ulcer Treatment at Rejuvence Clinic
Advanced wound healing using laser, LED, regenerative medicine and surgical expertise Rejuvence Clinic provides a specialist service for the assessment and treatment of chronic wounds and skin ulcers using a comprehensive, evidence-based approach.
We combine advanced laser and light therapies, expert tissue viability care, objective wound measurement, innovative regenerative medicine, and—where appropriate—surgical intervention. Our focus is on understanding why healing has stalled and delivering bespoke treatment pathways designed to reduce inflammation, support tissue repair and achieve durable wound closure.
Understanding Chronic Wounds & Ulcers
A wound is considered chronic when it fails to progress through the normal stages of healing within an expected timeframe. Rather than a single cause, chronic wounds usually arise from a combination of local and systemic factors.
These may include:
- Impaired circulation
- Persistent inflammation
- Pressure or friction
- Autoimmune or inflammatory disease
- Diabetes or metabolic disease
- Previous trauma, surgery or abnormal scar biology
Chronic wounds can be painful, restrictive and distressing, often affecting mobility, independence and quality of life. Repeated dressing changes alone are frequently insufficient without specialist assessment and targeted intervention.
Conventional Wound Care Pathways (Including NHS Care)
In standard community and hospital wound-care pathways, management typically focuses on:
- Regular dressing changes
- Pressure offloading where appropriate
- Infection control
- Ongoing monitoring
While this approach is essential, wounds may fail to heal if:
- Chronic inflammation is not adequately addressed
- Tissue perfusion remains poor
- Scar tissue biology is abnormal
- Healing progress is not measured objectively
Patients are often referred for specialist input when wounds do not improve despite prolonged standard care.
Chronic Wound & Ulcer Care at Rejuvence Clinic – Our Specialist Approach
At Rejuvence Clinic, we take a multidisciplinary, problem-solving approach to wound care. Rather than treating wounds in isolation, we assess the wound bed, surrounding skin, scar behaviour and systemic contributors to delayed healing.
Our integrated service includes:
- Dermatology-led assessment
- In-house tissue viability nurse expertise
- Advanced laser and LED therapies
- Objective wound tracking using 3D imaging technology
- Regenerative medicine where appropriate
- Surgical input when indicated
This allows us to tailor treatment to the biology of the wound, not just its appearance.
Tissue Viability Expertise & Advanced Wound Assessment
Our in-house tissue viability nurse provides specialist assessment of:
- Wound depth and tissue quality
- Inflammatory activity and exudate
- Peri-wound skin health
- Pressure and mechanical factors
This expertise is essential for long-standing or complex wounds and allows for appropriate dressing selection, escalation of care and structured monitoring.
Objective Wound Monitoring with 3D Imaging Technology
We use 3D wound measurement technology to accurately track:
- Surface area
- Depth
- Volume
- Rate of healing over time
Published wound-care research shows that objective measurement improves outcomes, enabling clinicians to adjust treatment plans based on measurable progress rather than visual estimation alone.
Venous & Arterial Ulcers – Specialist Assessment and Treatment
Chronic leg ulcers are commonly categorised as venous ulcers or arterial ulcers, each with distinct causes and treatment considerations. Accurate diagnosis is critical, as management strategies differ significantly.
At Rejuvence Clinic, venous and arterial ulcers are managed within a specialist, multidisciplinary framework, combining dermatology, tissue viability expertise, advanced light and laser therapies, regenerative medicine and close collaboration with wider medical care where required.
Venous Ulcers
Venous ulcers are the most common type of chronic leg ulcer and arise from chronic venous insufficiency, where impaired blood return leads to increased pressure within the veins. This results in ongoing inflammation, skin breakdown and delayed healing, typically around the lower leg or ankle.
Venous ulcers are often associated with:
- Swelling and skin discoloration
- Eczema-like inflammation around the wound
- Fibrosis and skin hardening
- Prolonged healing times and recurrence
Treatment of Venous Ulcers at Rejuvence Clinic
In addition to standard principles such as compression (where appropriate and safe), our focus is on modifying the wound environment and inflammatory burden.
Treatment may include:
- Aerolase® Neo Nd:YAG laser to reduce inflammation and improve local microcirculation
- Dermalux® LED phototherapy to stimulate cellular repair and granulation tissue formation
- Advanced dressing protocols guided by tissue viability assessment
- Objective 3D wound measurement to monitor progress
- ExoSmart™ autologous exosomes as a regenerative adjunct in selected, non-healing ulcers
What Does the Research Say?
Published wound-care literature supports the use of Nd:YAG laser therapy in venous ulcers, showing improvements in microvascular circulation and reductions in chronic inflammatory signalling.
LED phototherapy, particularly red and near-infrared wavelengths, has been shown to:
- Accelerate wound closure
- Improve granulation tissue formation
- Reduce inflammation and pain
Emerging research into autologous exosomes highlights their role in angiogenesis, immune modulation and fibroblast activity, suggesting potential benefit in stalled venous ulcers where healing has plateaued.
Arterial Ulcers
Arterial ulcers develop due to reduced blood supply to the tissues, often related to peripheral arterial disease. These ulcers are typically more painful, slower to heal, and may occur on the toes, feet or pressure points.
They are frequently associated with significant underlying medical conditions, including cardiovascular disease and diabetes.
Important Disclaimer on Arterial Ulcers
Arterial ulcers always require careful medical assessment. In many cases, restoring blood flow through vascular management is the primary priority. Light, laser and regenerative therapies are adjunctive only and do not replace appropriate medical or vascular treatment.
At Rejuvence Clinic, arterial ulcers are treated only when it is safe and appropriate, often in coordination with the patient’s wider medical team.
Supportive Treatment of Arterial Ulcers at Rejuvence Clinic
Where clinically suitable, we may use supportive therapies aimed at optimising the local wound environment, including:
- Dermalux® LED phototherapy, particularly near-infrared wavelengths, to support cellular metabolism and tissue oxygen utilisation
- Carefully selected Nd:YAG laser therapy in specific cases to reduce inflammatory burden
- Advanced wound dressings and tissue viability-led care
- Objective monitoring using 3D wound measurement
What Does the Research Say?
The literature consistently emphasises that adequate blood supply is fundamental to healing arterial ulcers. However, research also suggests that photobiomodulation (LED therapy) may:
- Improve mitochondrial activity in hypoxic tissue
- Support cellular energy production
- Reduce inflammatory stress in compromised wounds
Early research into autologous exosomes in ischaemic wound environments suggests potential roles in angiogenic signalling and immune modulation, but these approaches must always be used with caution and appropriate medical oversight.
Advanced Light & Laser Therapy for Chronic Wounds
Aerolase® Neo Nd:YAG Laser for Wound Healing
Aerolase® Neo is a 1064 nm Nd:YAG laser delivering ultra-short pulses of energy without damaging the skin surface. In wound care, it helps:
- Reduce chronic inflammatory signalling
- Improve local circulation
- Enhance tissue oxygenation
- Support progression through healing phases
Treatment is non-contact, non-invasive and well tolerated, even in fragile skin.
Dermalux® LED Phototherapy for Wound Healing
Dermalux® LED phototherapy uses clinically proven wavelengths of light to stimulate cellular repair and reduce inflammation.
Research on Individual Wavelengths
- Red light (630–660 nm): stimulates fibroblast activity, collagen synthesis and epithelial repair
- Near-infrared light (830–850 nm): penetrates deeper tissue, improving mitochondrial activity, blood flow and oxygen delivery
- Blue light (415 nm): offers antimicrobial and anti-inflammatory effects in selected wounds
Clinical studies show that combining red and near-infrared wavelengths can:
- Accelerate wound closure
- Improve granulation tissue
- Reduce pain and inflammation
Advanced Regenerative Medicine for Chronic Wounds
ExoSmart™ Autologous Exosomes
Rejuvence Clinic is one of the first clinics in the UK to offer the ExoSmart™ autologous exosome system, reflecting our leadership in regenerative medicine.
Exosomes are microscopic biological messengers involved in cell communication, immune modulation and tissue repair. ExoSmart™ isolates these from the patient’s own biological material.
Research suggests exosomes may:
- Promote angiogenesis
- Support fibroblast and keratinocyte function
- Modulate chronic inflammation
At Rejuvence Clinic, ExoSmart™ is used adjunctively, alongside advanced wound care, laser and LED therapy.
Surgical Approaches to Chronic Wounds & Abnormal Healing
While many chronic wounds respond to non-invasive and regenerative approaches, surgery may sometimes be required, particularly when abnormal scar tissue or wound architecture prevents healing.
We have extensive in-house experience in managing complex keloid and hypertrophic scars, which often coexist with or contribute to chronic wound problems.
Surgical intervention may be considered when:
- Fibrotic or non-viable tissue prevents closure
- Abnormal scarring perpetuates inflammation
- Structural correction is required
When surgery is used, it is always integrated into a broader treatment strategy, including laser, LED and regenerative therapies, to reduce recurrence and optimise outcomes.
Our Doctors
Dr Naeem Mitha – Specialist in Dermatology
Dr Mitha leads dermatology and complex wound care at Rejuvence Clinic, with expertise in inflammatory, autoimmune and scar-related skin conditions.
Dr Ghani – Expert in Regenerative Medicine
Dr Ghani is an expert in regenerative and autologous biological therapies, with a particular focus on advanced exosome systems and personalised treatment design.
Tissue Viability Nurse
Our in-house tissue viability nurse plays a central role in assessment, dressing selection, monitoring and patient education.
Book a Chronic Wound or Ulcer Assessment
If you are struggling with a wound or ulcer that is slow to heal, expert help is available. A comprehensive assessment can identify barriers to healing and open the door to advanced treatment options.













