Joint Injections - Knees

      
   4.8470 reviews

Specialist Knee Joint Injections in London

At Rejuvence Clinic, we provide diagnosis-led knee injection treatments for pain, swelling and reduced mobility. All injections are selected following careful clinical assessment and, where appropriate, ultrasound guidance, supporting safe symptom relief and structured rehabilitation.

Knee Joint Injections

Knee pain and swelling are common causes of reduced mobility and functional limitation. Symptoms may arise from joint degeneration, inflammation of the surrounding bursae, ligament injury, or accumulation of excess joint fluid (effusion).

While many knee conditions improve with physiotherapy, strengthening and activity modification, knee injections can play an important role in symptom management when pain or swelling persists.

At Rejuvence Clinic, knee injections are offered as part of an evidence-based treatment plan tailored to the underlying diagnosis and individual patient needs.

Knee Conditions We Treat

Injection therapy may be considered for:

Knee Effusion
(Joint Swelling)

Patellar Bursitis (Prepatellar Bursitis)

Knee
Osteoarthritis

Selected sports-related knee ligament injuries

Corticosteroid (Steroid) Injections

Corticosteroid injections are commonly used to manage inflammatory knee conditions. They work by reducing inflammatory activity within the joint or surrounding soft tissues, helping to relieve pain and swelling in the short to medium term.

In knee effusion, steroid injections may be used after aspiration to reduce ongoing inflammation. For patellar bursitis, steroid injections can help settle local inflammation when conservative measures such as rest and compression have not been sufficient. In knee osteoarthritis, steroid injections are frequently used to manage pain flares and improve mobility, particularly in patients who are not yet considering surgical options.

Steroid injections are used judiciously and are typically combined with physiotherapy and lifestyle modification rather than used as a long-term standalone treatment.

Summary – Steroid Injections

Reduce pain and inflammation
Commonly used in knee effusion and bursitis
Effective for short-term symptom control in knee arthritis
Best used alongside rehabilitation

Hyaluronic Acid Injection (Ostenil Plus®)

Hyaluronic acid injections aim to improve joint lubrication and reduce mechanical pain associated with cartilage wear. Ostenil Plus is a high-purity formulation used in degenerative joint disease.

In the knee, hyaluronic acid injections are widely used for knee osteoarthritis, with evidence suggesting improvements in pain and function in selected patients, particularly in mild to moderate disease. They may be considered where a non-steroidal option is preferred or where repeated steroid injections are not appropriate.

Hyaluronic acid injections are not routinely used for patellar bursitis or acute knee effusion unless degenerative joint changes are contributing to symptoms.

Summary – Hyaluronic Acid

Improves joint lubrication and shock absorption
Evidence-based option for knee osteoarthritis
Non-steroidal treatment
Variable response depending on disease stage

Hydrodistension (Not Routinely Used for Knee Conditions)

Hydrodistension is primarily used in frozen shoulder and is not routinely performed for knee effusion, bursitis or knee arthritis. It is not considered a standard treatment for knee joint pathology.

Summary – Hydrodistension

Not routinely used for knee conditions
Alternative treatments preferred
* Diagnosis-led decision making

Aspiration (Knee Joint or Bursa Aspiration)

Aspiration involves the removal of excess fluid from the knee joint or a swollen bursa. This can reduce pain caused by pressure and improve movement. Aspiration may also provide diagnostic information when inflammatory or infective causes are suspected.

In knee effusion, aspiration is commonly performed to relieve swelling and may be combined with injection therapy. In patellar bursitis, aspiration may be considered where swelling is significant or recurrent.

Summary – Joint Aspiration

Reduces pressure and swelling
Useful in knee effusion and bursitis
May assist diagnosis
* Often combined with injection treatment

Regenerative Medicine and Knee Ligament Injuries (ExoSmart™)

Autologous exosome-based injections (ExoSmart™) are an emerging area of regenerative medicine, using biologically active extracellular vesicles derived from a patient’s own blood sample. These vesicles are involved in cellular communication and inflammatory modulation.

Clinical interest includes sports-related knee ligament injuries, such as low-grade collateral ligament injuries and chronic ligament strain, where inflammation and delayed healing may limit recovery. Early laboratory and clinical studies suggest that exosome-based therapies may help modulate inflammation and support tissue repair processes, potentially improving pain and function in selected patients.

However, this remains an evolving area of medicine. While early results are encouraging, high-quality long-term clinical evidence is still developing. At Rejuvence Clinic, this option is offered only after careful assessment and informed discussion, and outcomes may vary.

Summary – Autologous Exosome Injection

Patient-derived regenerative treatment
Considered in selected sports-related knee ligament injuries
Emerging evidence suggests potential improvement in pain and function
Individualised patient selection with informed consent

Your Knee Injection Specialist

Mr Ameerudhin Ahamed

MBBS, MRCS, FRCS, PG Cert (MSK USGI) Consultant Trauma & Orthopaedic Surgeon Barts Health NHS Trust

Mr Ameerudhin Ahamed is a GMC-registered consultant orthopaedic surgeon with extensive experience in musculoskeletal medicine and ultrasound-guided injections. He qualified with an MBBS in 2000 and has held full GMC registration since 2007.

He completed advanced postgraduate training in Trauma and Orthopaedic Surgery across major London hospitals, including the Royal National Orthopaedic Hospital, Stanmore, and was awarded FRCS (Trauma & Orthopaedics) in 2016. He also holds a Postgraduate Certification in Musculoskeletal Ultrasound-Guided Injection.

At Rejuvence Clinic, Mr Ahamed provides specialist assessment and ultrasound-guided knee injections, integrating injection therapy into a broader care plan that may include physiotherapy, strengthening programmes and return-to-sport guidance.

Are knee injections painful?

Most patients experience brief discomfort. Ultrasound guidance helps improve accuracy and comfort.

How long do knee steroid injections last?

Relief varies, but benefits may last weeks to months, particularly when combined with physiotherapy.

Can injections cure knee arthritis?

Injections help manage symptoms but do not reverse arthritis. They are used to improve function and quality of life.

Is aspiration safe for knee swelling?

Aspiration is commonly performed and generally safe when done by experienced clinicians, with risks discussed during consultation.

Are regenerative injections proven for knee ligament injuries?

Research is ongoing. Early studies suggest potential benefit in selected cases, but outcomes vary and long-term evidence is still developing.

       
 Excellent4.8470 reviews
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   Sophia 
 12 September 2026
 
 
 Trustindex verifies that the original source of the review is Google. A massive thank you to Dr Ghani, Dr Mitha and Olga, who have looked after me for various cosmetic and hair procedure. I highly recommend this clinic to anyone looking for professional, knowledgeable and caring doctors and staff. The reception team are also absolutely lovely,  polite, welcoming and friendly.
  
 
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   Arpan Kumar 
 11 September 2026
 
 
 Trustindex verifies that the original source of the review is Google. The doctor and healthcare professional doing the surgery were lovely and made me feel comfortable throughout the procedure
  
 
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   Bisi Dauda 
 11 September 2026
 
 
 Trustindex verifies that the original source of the review is Google. What an incredible experience! The modern facilities at Rejuvence Clinic are state-of-the-art. The staff's professionalism and the personalized treatment I received were outstanding. Follow-up care was thorough, and the aftercare support was reassuring.
  
 
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   THY 
 11 September 2026
 
 
 Trustindex verifies that the original source of the review is Google. I can't thank Rejuvence enough for their brilliant service! My steroid injections eased my pain significantly. The team's professionalism and the state-of-the-art facilities were impressive. The follow-up care was just the cherry on top! 🌟
  
 
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   Jack Ho 
 10 September 2026
 
 
 Trustindex verifies that the original source of the review is Google. The nurses are very helpful and Dr Sam Ghani is thoughtful and understands my needs for scar removal.
  
 
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   Mahamed Hagar 
 10 September 2026
 
 
 Trustindex verifies that the original source of the review is Google. Rejuvence Clinic exceeded my expectations! The keloid removal was a breeze, and the staff's professionalism was top-notch. Follow-up care was attentive and reassuring. Truly a fantastic experience from start to finish! Dr Ghani and Paige thank you.
  
 
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   Tochi Madubuike 
 10 September 2026
 
 
 Trustindex verifies that the original source of the review is Google. Absolutely delighted with Rejuvence! The steroid injections were super effective, and the staff's professionalism was evident from start to finish. Their follow-up care was incredibly thorough. I can't recommend them enough for anyone in need!
  
 
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   Aziah Brown 
 8 September 2026
 
 
 Trustindex verifies that the original source of the review is Google. Amazing experience, all the staff are kind and helpful would recommend if need any cosmetic surgery done.
  
 
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   Daniel Brandão 
 6 September 2026
 
 
 Trustindex verifies that the original source of the review is Google. I saw Doctor Sam Ghani for my alopecia problem and he was amazing. The treatment was effective. All the staff is friendly, helpful and professional. Highly recommend.
  
 
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   Kurt King 
 3 September 2026
 
 
 Trustindex verifies that the original source of the review is Google. Dr Ghani was really informative and took the time to answer all of my questions and concerns. I left the clinic feeling like I actually understood my options and could make the right decision about what treatment to have. Really appreciated him taking the time to explain everything properly. I’ll definitely be back and would happily recommend him to anyone considering treatment.

Authored by:

Dr Samuel Ghani

MBBS BSc MRCSEd FRCEM MSc Aesthetic Medicine

GMC: 6103460

Clinically reviewed by:

Mr Ameerudhin Ahamed

MBBS, MRCS, FRCS, PG Cert (MSK USGI)

GMC: 6093057

References & Further Reading

1. NICE CKS. Knee pain and swelling: assessment and management. 2. NICE CKS. Bursitis – prepatellar: management. 3. McAlindon TE et al. Intra-articular corticosteroid injections for knee osteoarthritis. JAMA. 4. Bannuru RR et al. Hyaluronic acid injections for knee osteoarthritis. Osteoarthritis and Cartilage. 5. Li Z et al. Extracellular vesicles and musculoskeletal tissue repair. Stem Cell Research & Therapy.