Psoriasis Treatment at Rejuvence Clinic
Advanced psoriasis care using targeted Exciplex® UVB and next-generation autologous exosome therapy
Rejuvence Clinic offers specialist, evidence-based psoriasis treatment using precision UVB phototherapy, advanced laser and LED technologies, and cutting-edge autologous exosome regenerative medicine.
We are proud to be one of the first clinics in the UK to introduce the ExoSmart™ autologous exosome system, reflecting our long-standing commitment to innovation, safety and personalised care for complex autoimmune skin conditions.
Our approach is designed to reduce inflammation, improve symptoms, and move patients away from long-term reliance on harsh, steroid-dependent treatment pathways wherever possible.
Understanding Psoriasis
Conventional Psoriasis Treatment Pathways (Including NHS Care)
In traditional dermatology settings, including NHS services, psoriasis is commonly managed using a stepwise approach. Initial treatment often involves topical anti-inflammatory therapies. If disease becomes more extensive or persistent, patients may be referred for whole-body ultraviolet light therapy. In more severe cases, systemic immune-modulating treatments may be considered.
While these approaches are well established, they may present challenges such as:
Long-term dependence on topical steroid-based treatments
Exposure of unaffected skin to ultraviolet light
Systemic side effects in some patients
Limited flexibility for children or for difficult areas such as the scalp
Many patients seek alternatives that are effective yet gentler, particularly for long-term management.
Psoriasis Treatment at Rejuvence Clinic – Our Philosophy
At Rejuvence Clinic, we take a precision-led, steroid-sparing approach to psoriasis. Our focus is on treating affected skin accurately, calming immune-driven inflammation, and supporting skin recovery—while minimising unnecessary exposure and long-term risks.
We are particularly known for:
Combining established dermatology treatments with regenerative innovation
Developing bespoke treatment pathways for difficult or treatment-resistant psoriasis
Actively exploring alternatives to long-term, steroid-dependent care
Our doctors work closely together to design individualised treatment regimens, often combining multiple complementary technologies.
Exciplex® UVB Light Therapy for Psoriasis
Exciplex UVB is a cornerstone of our psoriasis treatment protocols. It delivers targeted narrowband UVB light directly to psoriasis plaques, avoiding exposure of surrounding healthy skin.
This approach helps to:
- Suppress inflammatory immune cells in the skin
- Slow abnormal skin cell turnover
- Reduce redness, thickness and scaling
- Improve symptoms safely over time
Treatment is pain-free, non-invasive and well tolerated, making it suitable for long-term use and paediatric patients.
What Does the Research Say About Exciplex® UVB for Psoriasis?
A substantial body of dermatology research supports narrowband UVB as an effective treatment for plaque psoriasis. International guidelines, including those from the British Association of Dermatologists, recognise UVB phototherapy as a first-line option for moderate disease.
Targeted UVB systems have been shown to:
- Achieve strong clearance rates
- Reduce cumulative ultraviolet exposure
- Improve safety compared to whole-body UVB
- Allow treatment of difficult sites, including the scalp
Paediatric studies confirm that supervised narrowband UVB is safe, effective and well tolerated in children, with minimal side effects.
Aerolase® Neo Nd:YAG Laser for Psoriasis
Aerolase Neo is a 1064 nm Nd:YAG laser that delivers ultra-short pulses of energy into the skin without damaging the surface. In psoriasis, it is used to help reduce inflammation, redness and vascular activity within plaques.
It works by:
Targeting inflammatory blood vessels that sustain plaques
Reducing inflammatory signalling within the skin
Improving skin comfort and appearance
The treatment is non-contact, non-invasive and suitable for sensitive or inflamed skin.
What Does the Research Say About Aerolase Neo Nd:YAG for Psoriasis?
Published clinical studies on Nd:YAG laser use in psoriasis demonstrate:
Reduction in plaque redness and thickness
Improvement in scaling and inflammation
Good tolerability with minimal adverse effects
Nd:YAG laser therapy is increasingly recognised as a useful adjunctive treatment, particularly for patients seeking non-pharmacological options.
Dermalux® LED Phototherapy for Psoriasis
Dermalux LED uses clinically proven wavelengths of light to support skin repair and reduce inflammation. It is commonly used alongside Exciplex UVB or laser therapy.
LED phototherapy helps to:
Reduce inflammatory cytokine activity
Improve cellular repair processes
Support skin barrier recovery
What Does the Research Say About Dermalux LED for Psoriasis?
Dermatology research shows that specific LED wavelengths exert anti-inflammatory effects and enhance skin healing. Studies report:
Improved skin repair
Reduced inflammation
Excellent safety profile
LED therapy is widely used as a supportive treatment to enhance overall outcomes.
Advanced Regenerative Medicine for Psoriasis
ExoSmart™ Autologous Exosomes
Rejuvence Clinic is one of the first clinics in the UK to offer the ExoSmart™ autologous exosome system. This reflects our extensive experience with high-end autologous blood-derived concentration platforms, including Magellan and Angel Arthrex systems, and our leadership in regenerative medicine. Exosomes are microscopic biological messengers involved in cell communication, immune modulation and tissue repair. ExoSmart™ isolates these signalling particles from the patient’s own biological material.
How ExoSmart™ Is Different
Unlike many commercially available exosome products derived from plant or animal sources, ExoSmart™ is:
Autologous (patient-derived)
- Designed to reduce immune incompatibility
- Aligned with personalised regenerative medicine principles
This makes it particularly attractive for autoimmune and inflammatory conditions.
What Does the Research Say About Autologous Exosomes in Psoriasis?
Scientific literature increasingly highlights the role of exosomes in regulating immune responses and inflammation.
Early research suggests they may:
Reduce inflammatory immune signalling
Support tissue repair and regeneration
Help restore skin homeostasis
While this remains an evolving field, it aligns closely with modern strategies for managing autoimmune disease.
Scalp Psoriasis & Inflammatory Scalp Conditions
Scalp psoriasis is often resistant to conventional treatments due to hair density and limited penetration. At Rejuvence Clinic, we have seen success using combination treatment strategies, particularly for severe scalp disease.
These may include:
Exciplex UVB for targeted immune modulation
ExoSmart™ autologous exosomes to support regeneration
Aerolase Neo for inflammation reduction
We have also applied similar approaches to other autoimmune and inflammatory scalp conditions, including alopecia areata and seborrhoeic dermatitis.
Needle-Free Delivery with TargetCool™
Using TargetCool™ technology, we can deliver certain regenerative treatments, including ExoSmart™, without needles.
This cold-assisted delivery method:
Improves comfort
Enhances uptake of regenerative therapies
Is particularly beneficial for scalp treatments and children.
Safety of Exciplex® UVB and Dermalux® LED in Children
Safety is central to our practice. Both Exciplex UVB and Dermalux LED have excellent safety profiles and are supported by paediatric dermatology research.
Studies show that:
Narrowband UVB is safe and effective in children with psoriasis
Side effects are typically mild and temporary
No evidence of long-term harm when appropriately supervised
The pain-free nature of Exciplex UVB makes it especially valuable in children, allowing effective symptom control without distress.
Our Doctors
Dr Naeem Mitha – Specialist in Dermatology
Dr Mitha leads dermatology services at Rejuvence Clinic and specialises in autoimmune, inflammatory and complex skin conditions, including psoriasis. He has extensive experience in advanced phototherapy and laser-based dermatology.
Dr Ghani – Expert in Regenerative Medicine
Dr Ghani is an expert in regenerative and autologous biological therapies, with a particular focus on advanced exosome systems and personalised treatment design.
Together, Dr Mitha and Dr Ghani work closely to develop bespoke, innovative treatment pathways for patients with difficult autoimmune conditions—always with the aim of improving outcomes while reducing dependence on long-term steroid-based care.
Book a Psoriasis Consultation at Rejuvence Clinic
If psoriasis is affecting your comfort, confidence or quality of life, expert help is available. Our team will assess your condition in detail and create a personalised treatment plan tailored to your needs.
