Skin Care – Zein Obagi
The use of face creams, cleansers and scrubs in the pursuit of younger looking skin is a multi billion pound industry and influenced heavily by industry marketing and celebrity endorsements. Unfortunately our choice of creams to use on our face is not evidence based – there is no scientific evidence to prove its efficacy. As a result often we are left disappointed with the results and find ourselves moving from product to product and brand to brand. Good skin is considered to be smooth, even in colour, firm and tight, well hydrated, tolerant, contour rich and free of active disease. Do you have good skin?
How does skin change over the years?
By the age of 30 our skin often enters an inactive phase and the complex machinery of maintaining good skin that is hard at work in our younger years starts to grind to a halt. This results in irregular skin cell function, weakened and impaired barrier function, changes in skin texture and laxity and wrinkles as a result of damage to existing collagen and elastin alongside reduced production. Despite the effects of ageing, it is possible to keep the skin functioning properly throughout life.
Rejuvence Philosophy
At Rejuvence we have a thorough understanding of essential and supportive agents necessary in an effective skin care program. We are also great believers in only using products that have been scientifically proven to work. Hence we specialise in the prescription and use of products from the Zein Obagi line. All ZO products are based around the use of essential and supportive components and have yielded excellent results. We recommend all our clients change their daily skin care regime to ZO and we are sure they won’t be disappointed.
Ideally, before commencing any skin care products, you should research and analyse the component ingredients to ensure that only products proved to be beneficial and therapeutic are used. Unfortunately this can be overwhelming especially since there is so much unclear and misleading information. It is important to realise that the majority of products provide quick gratification through looking, smelling and feeling good. However, they yield no visible or lasting benefit. Often components used to make products comfortable are counterproductive for your skin. Unfortunately most currently marketed anti-ageing products are useless and do not deliver. This is usually because their active ingredient is ineffective, too low in concentration or too large a molecule to penetrate the skin.
There are a core group of essential components that have been scientifically shown in multiple studies to have beneficial effects. These components are the only known substances that have been shown to be able to return skin to its best possible original state. These essential components have a number of effects. They enhance natural exfoliation of the skin. They ensure proper barrier function by way of restoring the correct balance between water, lipids and protein in the skin. They even the colour tone of the skin. They stimulate the repair and production of new collagen and elastin to improve skin vitality, lines and wrinkles. They improve hydration of the skin by increasing the production of glycosaminoglycans such as hyaluronic acid as well as repair DNA.
The most common essential components of any beneficial skin care package are vitamin A derivatives including tretinoin and retinol, hydroquinone, antioxidants, DNA repair agents, anti-inflammatory agents and growth factors.
Tretinoin benefits both the upper and deeper layers of the skin. It repairs damaged epidermal cells and improves natural hydration as well increase epidermal thickness. In the deeper dermis tretinoin increases collagen and elastin as well as hyaluronic acid. The higher the strength of tretinoin, the deeper it penetrates, the more impressive are its effects. However, it is associated with initial peeling and redness that requires a few weeks to get used. Retinol is less irritating but not as potent.
Hydroquinone prevents the formation of new melanin and is used to treat pigmentation problems. The effectiveness of hydroquinone is further enhanced when combined with tretinoin. It has a bleaching effect when used in isolation. It has a blending effect when used in combination with tretinoin to help even out colour tone.
As a byproduct of certain cellular activities free radicals are produced and can trigger a series of reactions that can cause cell damage. Antioxidants remove these free radicals and limit the extent of any damage. Examples of antioxidants are alpha-lipoid acid, glutathione, idebenone, ubiquinone, vitamin C, vitamin E and vitamin B.
Ageing is believed to be a consequence of an accumulation of unprepared naturally occurring DNA damage. DNA repair agents include Oxo-guanine glycosylase-1, Ultraviolet endonuclease, Photolyase, Natural DNA repair precursors.
Growth factors have been shown to repair photo damage. However, there is controversy associated with the use of products containing human growth factors where as non-human and synthetically sourced growth factors have much better safety profiles.
There are a series of well recognised components that have are considered mildly therapeutic and have been shown to be very effective when used in combination with essential agents. Supportive agents include alpha-hydroxy acids, beta-hydroxy acids, non-hydroquinone pigment-stabilising agents and disease specific agents.
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A. B. London10 October 2026Trustindex verifies that the original source of the review is Google.
I was looking for a clinic offering Sciton BBL treatments in Canary Wharf, close to my workplace, when I came across Rejuvence Clinic. Their prices were much more affordable compared to other clinics in the City, so I decided to give them a try. I booked a treatment for vascular redness and rosacea, as the redness tends to flare up from time to time. My treatment was carried out by Kurt, who was incredibly thorough and attentive throughout. To my surprise, by the time I got home, I could already see a noticeable improvement! I’m really happy with my choice and would definitely recommend Kurt. The reception staff were also very friendly and welcoming, which made the whole experience even better!Posted on Google![]()
S H9 October 2026Trustindex verifies that the original source of the review is Google.
I had a huge keloid scar removed here. The doctors are professional and polite, and the clinic is very clean and pleasant. I would highly recommend this clinic as the doctors are friendly and make you feel welcome.Posted on Google![]()
Aaron8 October 2026Trustindex verifies that the original source of the review is Google.
Absolutely thrilled with Rejuvence! The steroid injections were highly effective, and the staff's professionalism was superb. Everything was personalized to my needs in a clean and welcoming environment. I couldn't ask for better!Posted on Google![]()
Julien Feild3 October 2026Trustindex verifies that the original source of the review is Google.
I've been coming here for a year now the service is fabulous and in particular I'd like to highlight Olga who was absolutely a star when dealing with me and administering the PRP - Flawless!!!Posted on Google![]()
Prem Gurung3 October 2026Trustindex verifies that the original source of the review is Google.
The treatment at Rejuvence was a life-changer. My hair is growing back wonderfully! The staff's professionalism was evident from start to finish, making the whole experience so reassuring. Absolutely recommend this clinic!Posted on Google![]()
Paula St Ange3 October 2026Trustindex verifies that the original source of the review is Google.
My keloid removal went flawlessly and the results are phenomenal. The team was incredibly professional and made everything so easy. Can't recommend them enough for keloid treatment!Posted on Google![]()
jamker01 October 2026Trustindex verifies that the original source of the review is Google.
Been having my Keloid treated here at Rejuvence, the service from the administration to the doctors here have been amazing made me feel very comfortable and calm very happy with my results and definitely recommend , Dr Ghana , Paige Rita, & others for your skills upon what you do here thank you , JmainePosted on Google![]()
Ling Jiang1 October 2026Trustindex verifies that the original source of the review is Google.
What a fantastic place! Rejuvence Clinic combines professionalism with outstanding follow-up care. The facilities are modern and well-equipped, making the whole experience seamless and stress-free. Can't praise them enough for their amazing service!Posted on Google![]()
Anna Villocino29 September 2026Trustindex verifies that the original source of the review is Google.
Everyone is professional,this is my 4th session in this clinic and I'm glad with the progress so far 😍Posted on Google![]()
Jolyon Ng26 September 2026Trustindex verifies that the original source of the review is Google.
Incredible experience at Rejuvence! The keloid removal was painless, and the results are beyond my expectations. The clinic is spotless, and the team is super professional. Their modern facilities are top-notch. Highly recommend!













