Vitiligo Treatment at Rejuvence Clinic
Advanced, evidence-based care using Exciplex® UVB and regenerative innovation
At Rejuvence Clinic, we offer specialist, personalised treatment for vitiligo, focusing on evidence-based phototherapy, steroid-sparing medical care and regenerative dermatology. Vitiligo is a complex autoimmune condition, and successful management requires a tailored, long-term strategy rather than a one-size-fits-all approach.
Our vitiligo services are led by Dr Naeem Mitha, specialist in dermatology, working closely with Dr Ghani, an expert in regenerative medicine, to develop bespoke treatment pathways for both adults and children.
Vitiligo Treatment at Rejuvence Clinic – Overview of Our Approach
Vitiligo management at Rejuvence Clinic begins with a detailed dermatological assessment, supported by advanced imaging where appropriate. Treatment pathways are designed to:
- Stimulate repigmentation
- Suppress autoimmune-driven inflammation
- Preserve melanocyte function
- Minimise reliance on long-term steroid use
Our vitiligo treatment options include:
- Exciplex® UVB phototherapy (cornerstone treatment)
- Steroid-sparing topical therapies
- Regenerative medicine approaches, including autologous exosomes
- Supportive skin-barrier optimisation
Where appropriate, treatments may be combined to optimise outcomes and improve long-term disease stability.
Understanding Vitiligo
Vitiligo is an autoimmune skin condition characterised by the loss of melanocytes, the pigment-producing cells of the skin. This results in well-defined white or hypopigmented patches that may affect the face, body, scalp and mucosal surfaces.
The condition is not contagious, but it can have a significant psychological impact. Vitiligo may begin at any age and often follows an unpredictable course, with periods of stability and progression.
What Causes Vitiligo?
Vitiligo is driven by immune-mediated destruction of melanocytes. Genetic susceptibility plays a role, and vitiligo is commonly associated with other autoimmune conditions.
Triggers may include:
- Physical or emotional stress
- Skin trauma (Koebner phenomenon)
- Hormonal changes
- Certain medications or injections
Understanding the underlying immune activity is key to selecting appropriate treatment.
Exciplex® UVB Phototherapy for Vitiligo
Exciplex® UVB is a targeted ultraviolet B phototherapy system and is the foundation of vitiligo treatment at Rejuvence Clinic.
Exciplex works by:
- Suppressing autoimmune activity in affected skin
- Stimulating melanocyte migration from hair follicles
- Promoting repigmentation while sparing surrounding healthy skin
Unlike older phototherapy systems, Exciplex delivers precise, targeted UVB, reducing cumulative UV exposure and minimising side effects.
What Does the Research Say About Exciplex® UVB for Vitiligo?
Extensive published research supports the use of targeted UVB phototherapy as a first-line treatment for vitiligo.
Clinical studies demonstrate:
- Higher repigmentation rates compared with non-targeted UVB
- Improved response in facial and focal vitiligo
- Enhanced outcomes when combined with topical therapies
- Excellent long-term safety profile
Targeted UVB is particularly effective in children and young adults, where early intervention can significantly improve outcomes.
Safety of Exciplex® UVB in Children
Exciplex UVB has a strong safety record in paediatric dermatology. It is:
- Completely pain-free
- Non-invasive
- Well tolerated by children
Published paediatric studies show minimal side effects, with no increased risk of scarring or pigmentary complications when delivered under medical supervision.
This makes Exciplex an excellent option for children with vitiligo, where long-term steroid use is often undesirable.
Vitiligo Following Steroid Injections (Hypopigmentation)
Localised hypopigmentation can occur as a side effect of intralesional steroid injections, particularly in patients with darker skin tones. This form of pigment loss is distinct from classical vitiligo but can be equally distressing.
At Rejuvence Clinic, we treat steroid-induced hypopigmentation using:
- Exciplex® UVB to stimulate melanocyte recovery
- Steroid-sparing topical therapies to support repigmentation
What Does the research say?
Published case series and clinical reports show that targeted UVB phototherapy can significantly improve steroid-induced hypopigmentation, particularly when treatment is started early. Combining UVB with non-steroidal topical support improves repigmentation while avoiding further melanocyte suppression.
Regenerative Medicine for Vitiligo
Regenerative medicine represents a promising adjunct in vitiligo management, particularly in stable or treatment-resistant disease.
Autologous exosomes are involved in:
- Cell-to-cell communication
- Immune modulation
- Tissue repair and regeneration
Early research suggests that regenerative approaches may help:
- Support melanocyte survival
- Improve the skin microenvironment
- Enhance response to phototherapy
At Rejuvence Clinic, regenerative treatments are used alongside Exciplex UVB, rather than as a replacement, to support repigmentation and long-term stability.
Vitiligo Affecting the Scalp
Vitiligo affecting the scalp can be challenging to treat due to hair density and follicular involvement. We have seen encouraging results using combinations of Exciplex UVB and regenerative approaches, particularly in patients with concurrent inflammatory scalp conditions.
Targeted delivery methods allow treatment without needles, improving comfort and compliance.
Medication Options for Vitiligo at Rejuvence Clinic
Medication may be used selectively as part of a broader treatment plan.
Options include:
- Steroid-sparing topical therapies
- Short-term medical support during active disease
Wherever possible, we prioritise phototherapy-led and regenerative strategies to minimise long-term medication dependence.
Our Doctors
Dr Naeem Mitha – Specialist in Dermatology
Specialist in dermatology with extensive experience in autoimmune and inflammatory skin conditions, including vitiligo. He leads vitiligo services at Rejuvence Clinic.
Dr Ghani – Expert in Regenerative Medicine
Expert in regenerative medicine, working closely with the dermatology team to develop innovative, bespoke treatment strategies for complex autoimmune skin conditions. Together, they design individualised treatment pathways focused on safety, efficacy and long-term outcomes.
Book a Vitiligo Consultation
Vitiligo treatment is most effective when started early and tailored to the individual. At Rejuvence Clinic, we combine advanced technology, clinical expertise and evidence-based care to deliver meaningful results.
