Anti Ageing
Advanced Anti-Ageing & Regenerative Treatments
Precision-Led. Evidence-Based. Results That Matter.
At Rejuvence Clinic, we deliver evidence-based anti-ageing treatments designed to target the biological causes of skin ageing — not just the visible symptoms. Our approach focuses on proven methods to improve collagen loss, skin laxity, thinning, pigmentation, inflammation and overall structural decline. Every treatment we offer is selected because it is shown to make a meaningful, measurable difference.
AI-Powered Skin Assessment
We use advanced AI technology and high-resolution facial analysis systems to assess every aspect of facial ageing. This includes skin quality, volume loss, texture changes, symmetry, pigmentation and structural support. Our intelligent diagnostic tools allow us to accurately map your ageing profile and identify the areas that require targeted intervention.
Precision Facial Analysis
Through detailed facial analysis, we create a bespoke anti-ageing strategy tailored specifically to you. AI-assisted evaluation ensures that we recommend only the treatments most likely to deliver significant, reproducible results — avoiding unnecessary procedures and focusing on what truly works.
Advanced Regenerative & Energy-Based Treatments
We offer a comprehensive range of premium treatments. This layered, strategic approach allows us to restore skin quality, improve firmness, enhance radiance and support long-term skin health.
How does the skin age?
Skin health and the maintenance of skin health involves numerous strategic cells and processes. Our skin is at its best while we are still children. Up to the age of 10 years skin can be defined as being smooth, even in colour, firm, tight, well moisturised, tolerant and the process of skin cell repair and regeneration is regular. There is no sebum (oil) production, no inflammation, no dryness and no sensitivity. During our teenage years skin health begins to deteriorate and function becomes altered. Our skin starts to produce sebum, becomes inflamed, and as a result we start to develop irregular textures and enlarged pores, acne, uneven skin colour, and a dull appearance.
By the age of 30, skin becomes inactive. The turnover of skin cells becomes extremely irregular. The skin’s barrier function becomes weak. A lack of cellular activity means critical structures within the skin become depleted, abnormal in structure and hence skin starts to develop lines and wrinkles. There are three main components of the skin that are the focus of the majority of anti ageing treatments. These are collagen, elastin and hyaluronic acid. Treatments that are aimed at increasing their levels as well as optimising the conditions for their production, repair, and regeneration produce the best anti ageing effects.
What happens to fat with ageing of the face?
As mentioned earlier facial ageing is a three-dimensional process. Below the skin of the face is a complex arrangement of self contained parcels of fat. These parcels of fat are arranged either side of the SMAS (muscular system of the face). The deep parcels of fat provide the mid-face with volume and youth. As we age the deep parcels of fat reduce and essentially deflate. This results in loss of volume of the mid-face. The superficial parcels of fat are more variable in their behaviour.
In some people the superficial fat parcels can increase in size and alongside weakened ligaments result in sagging of the mid-face and jawline producing tear troughs, nasolabial folds and jowls. In others the superficial fat parcels deflate with age, there is overall loss of volume in the face. The face can then take on a skeletonised facial appearance. A thorough understanding of the location of different parcels of fat and how they are behaving can lead to excellent results when using dermal fillers and fat transfer to restore balance and plump to the face.
Sciton Forever Young BBL™ — Signature Anti-Ageing Rejuvenation
Science-Driven. Long-Term Age Defiance. Visible, Youthful Skin.
At Rejuvence Clinic, Sciton Forever Young BBL™ (BroadBand Light) is one of our most advanced non-surgical anti-ageing treatments. This sophisticated light-based technology goes beyond surface correction, helping to restore clearer, firmer and more youthful-looking skin with minimal downtime. It is ideal for discerning clients seeking a premium, evidence-based treatment that can significantly delay — and in some respects reverse — visible signs of ageing over time.
How Forever Young BBL Works
Forever Young BBL delivers precise broad-spectrum light energy into the skin, gently stimulating collagen production and activating the skin’s natural repair processes. This supports improvements in tone, texture and elasticity while targeting pigmentation and vascular changes associated with ageing.
Published research, including a landmark Stanford University study in the Journal of Investigative Dermatology, demonstrated that regular BBL treatments can positively influence gene expression patterns linked to skin ageing — encouraging older skin to behave more like younger skin at a molecular level. This provides scientific support for its role in long-term skin rejuvenation.
Targeted Anti-Ageing Benefits
Over a course of treatments, Forever Young BBL can help to:
Reduce fine lines and early wrinkles
Improve uneven skin tone and pigmentation
Minimise sun damage and age spots
Reduce redness and visible vessels
Enhance skin firmness and elasticity
With regular maintenance, patients can preserve clearer, brighter and more resilient skin, helping to slow the progression of visible ageing.
A Premium, Evidence-Based Rejuvenation Experience
At Rejuvence Clinic, BBL treatments are guided by our AI-powered facial analysis and evidence-led treatment planning. We precisely assess pigmentation, collagen loss and vascular ageing to tailor your protocol for optimal, measurable results.
Forever Young BBL can be delivered as a standalone rejuvenation treatment or integrated into a comprehensive regenerative programme alongside exosomes, polynucleotides and advanced energy-based therapies — creating a strategic, long-term approach to refined anti-ageing.
Reverse Neo: Deep dermal skin rejuvenation combined with superficial skin resurfacing
Aerolase Era Elite is a fully ablative Erb:YAG laser suitable in all skin types thanks to its 300-microsecond pulse duration and precise depth control with no demarcation lines enabling bespoke skin resurfacing. It is similar to a Fraxel CO2 laser but is safer in darker skin types.
Aerolase Era Elite can be combined with Neo Elite to offer a fully ablative resurfacing treatment to help improve contours and poor skin texture and skin tone immediately following deep dermal collagen stimulation with Neo. The unique ‘Reverse Neo’ protocol combines Neo and Era in a single session and is considered to be the ultimate dermatological laser protocol. The ‘Reverse Neo’ protocol can be finished off with Target Cool delivered topical rejuvenating E50 Exosomes. This speeds up recovery and can help with redness and pigmentation.
Other treatment options include microneedling combined with Radio-Frequency Energy in the form of Sylfirm X in combination with Target Cool delivered topical rejuvenating E50 Exosomes.
More old school approaches to acne scar improvement includes chemical peels such as the ZO 3 Step Peel or Controlled Depth Blue Peel. Pigmentation can initially be addressed by incorporating hydroquinone into any bespoke skin care program in an attempt to bleach, and in combination with Vitamin A, blend the skin producing a more even skin tone and reduction in post-inflammatory hyperpigmentation scars.
Sylfirm X - Radio Frequency Microneedling for tighter skin
Microneedling is clinically proven to result in new collagen formation and rejuvenation of the skin. Radio Frequency devices result in the delivery of heat to the deeper layers of the skin, known as the dermis, resulting in denaturing (breakdown) of collagen and elastin. This is followed by new collagen and elastin formation making skin tighter. Sylfirm X combines radio frequency energy with microneedling, resulting in skin tightening with collagen induction. Sylfirm X is an alternative to Morpheus 8. The difference between these is that Sylfirm X has the option of using a continuous or pulsed radio frequency beam meaning it is safer to use in delicate areas, such as the upper and lower eyelids as well as helping with hyperpigmentation and redness. Sylfirm X is an excellent choice for non-surgical treatment of heavy eyelids (upper and lower), loose skin on the face and neck helping to address jowls and nasolabial folds, hyperpigmentation from scars and melasma as well as redness associated with rosacea.
©Photos courtesy of Sylfirm X. Individual results may vary.
LA EXO ExoGiov® Exosome Therapy
Advanced Non-Surgical Anti-Ageing
At Rejuvence Clinic, we offer LA EXO ExoGiov® Exosome Therapy as part of our premium, medically led regenerative anti-ageing programme. This advanced, non-invasive treatment is designed to improve skin quality at a cellular level — restoring firmness, luminosity and structural integrity without surgery or extended downtime.
How Exosomes Rejuvenate Ageing Skin
Exosomes are intelligent cellular messengers that stimulate repair and renewal within the skin. As collagen and elastin naturally decline with age, the skin becomes thinner, less elastic and more prone to fine lines, wrinkles and laxity.
ExoGiov® Bio-Pulsed Exosomes encourage fibroblasts to increase collagen production, enhance elastin activity and strengthen the dermal matrix. Rather than temporarily masking wrinkles, this treatment focuses on improving skin function and long-term structural support — resulting in smoother, firmer and more resilient skin.
Targeted Anti-Ageing Benefits for Skin
This treatment is designed to address the key biological drivers of skin ageing, including:
- Fine lines and dynamic wrinkles
- Early to moderate skin laxity
- Loss of collagen density and dermal thinning
- Reduced elasticity and firmness
- Dull, tired or lacklustre complexion
- Uneven skin texture and enlarged pores
- Sun-induced skin ageing
- Early inflammatory ageing (“inflammageing”)
- Decline in skin hydration and barrier strength
By supporting collagen types I and III and enhancing elastin production, skin appears smoother, denser and more youthful, with improved tone and radiance.
No Needle Target Cool™ Delivery
For patients who prefer a completely needle-free approach, we can combine exosome therapy with our No Needle Target Cool™ technology. This advanced cooling delivery system enhances absorption of regenerative actives without injections, discomfort or downtime — offering a refined and discreet anti-ageing solution.
Autologous Exosome Therapy
ExoSmart® with Angel Arthrex® Regenerative System
For patients seeking the highest level of regenerative anti-ageing available, Rejuvence Clinic offers Autologous Exosome Therapy using the ExoSmart® system, combined with the Angel Arthrex® Regenerative System.
A Personalised Regenerative Anti-Ageing Strategy
This advanced treatment harnesses your body’s own regenerative components. Using sophisticated concentration technology, we prepare a personalised exosome-rich solution designed to stimulate deep dermal renewal and structural rejuvenation.
Because the treatment is derived from your own biology, it is highly biocompatible and aligned with our evidence-based, natural rejuvenation philosophy.
Comprehensive Skin Anti-Ageing Benefits
The combined ExoSmart® and Angel Arthrex® protocol supports:
- Significant collagen stimulation and remodelling
- Increased dermal thickness and skin strength
- Reduction in deeper, static wrinkles
- Improved skin tightening and firmness
- Enhanced skin tone and texture uniformity
- Reduction in pigmentation irregularities
- Improved microcirculation and tissue vitality
- Greater skin resilience and long-term structural support
A Rare & Advanced Regenerative Offering
Rejuvence Clinic is proud to be one of the few clinics offering this highly specialised autologous exosome therapy in combination with the Angel Arthrex® system.
Our discerning patients choose this approach when seeking a premium, regenerative anti-ageing treatment designed to deliver measurable, long-term improvements in skin quality, firmness and overall youthful appearance.
Polynucleotide Skin Rejuvenation
Advanced Regenerative Anti-Ageing for Skin Quality
At Rejuvence Clinic, polynucleotide therapy forms a key part of our evidence-based regenerative anti-ageing portfolio. This advanced treatment is designed to improve skin strength, hydration and structural integrity from within — delivering refined, natural rejuvenation without adding artificial volume.
Polynucleotides are highly purified DNA fragments that stimulate the skin’s natural repair pathways. Supported by clinical research, they activate fibroblasts, promote collagen synthesis and help reduce low-grade inflammation associated with skin ageing. The result is progressive improvement in skin thickness, elasticity and overall dermal health.
Targeted Skin Anti-Ageing Benefits
Polynucleotide therapy is particularly effective for addressing:
- Fine lines and superficial wrinkles
- Crepey, thinning or fragile skin
- Loss of elasticity and firmness
- Under-eye ageing and delicate skin laxity
- Sun-induced skin damage
- Dehydrated or compromised skin barrier
- Ageing of the neck and décolletage
- Uneven texture and reduced skin smoothness
Rather than temporarily masking imperfections, polynucleotides enhance the skin’s ability to regenerate and strengthen itself. Over a carefully planned treatment course, patients typically notice firmer, smoother, brighter skin with improved resilience and hydration.
Exosomes vs Polynucleotides
A Precision-Led Regenerative Strategy
Both exosomes and polynucleotides are sophisticated regenerative anti-ageing treatments, yet they work through complementary mechanisms.
Exosomes act as advanced cellular messengers. They deliver growth factors and signalling molecules that instruct skin cells to repair, regenerate and function more youthfully. Their strength lies in enhancing communication within the skin to stimulate renewal.
Polynucleotides, by contrast, provide structural support and stimulation. They encourage collagen production, improve hydration and reinforce dermal strength, creating a healthier foundation for long-term skin quality.
In essence:
Exosomes initiate regeneration.
Polynucleotides reinforce and strengthen it.
Following detailed AI-supported facial analysis at Rejuvence Clinic, we determine whether one treatment — or a strategic combination — will deliver the most effective, measurable and elegant anti-ageing outcome for your skin.
Our approach remains consistent: clinically grounded, technologically advanced and tailored for discerning patients seeking refined, long-term rejuvenation.
Medical-Grade Skincare for Long-Term Anti-Ageing
At Rejuvence Clinic, we believe that exceptional anti-ageing results require both advanced treatments and a scientifically structured home skincare programme. We therefore recommend ZO® Skin Health, a medical-grade skincare range formulated to address key concerns such as fine lines, pigmentation, sun damage, uneven texture and loss of skin resilience. ZO® products are clinically supported, suitable for all skin types and integrate seamlessly with our in-clinic anti-ageing protocols.
Medical-Grade Skincare for Long-Term Anti-Ageing
Using our AI-powered facial analysis system, we objectively assess collagen loss, pigmentation, texture, pore size and photodamage. This allows us to precisely identify your individual skin ageing profile. We then match your findings with skincare products that have a strong scientific evidence base and published data supporting their effectiveness for specific anti-ageing concerns.
This data-driven approach ensures your skincare is not generic, but strategically selected to enhance treatment results, support collagen health and maintain long-term skin quality.
At Rejuvence Clinic, every recommendation is guided by evidence, precision and a commitment to refined, measurable outcomes.
Neo Hydrafacial - #Ultimate Neo Glow
At Rejuvence we are always looking to offer our clients innovative anti-ageing solutions by combining different treatments to offer something a little extra. Hydrafacial is the only hydradermabrasion procedure that combines cleaning, extraction and hydration simultaneously alongside a chemical peel, resulting in clearer, more beautiful skin with little to no downtime. The treatment is soothing, moisturising, non-invasive and generally non irritating. Results are often almost immediate. To take it to the next level, at Rejuvence we offer a Neo-Hydrafacial where we carry out a full face Aerolase Neo Elite laser treatment followed by a Hydrafacial. The Neo helps with a number of skin concerns including Acne, Acne Scarring, Hyperpigmentation, Redness & Rosacea as well as general facial rejuvenation. The result is the #ultimate Neo Glow! This combination is fantastic as a one off treatment and even better as part of a regular hydrafacial skin care routine.
Rejuvence Philosophy
At Rejuvence we have a thorough understanding of the processes involved in the ageing of the face. We are keen to emphasise the 3 dimensional nature of the ageing process and hence ageing at multiple levels need to be addressed in order to achieve good results. In addition we are passionate about using evidence based treatments. Over recent years doctors have realised that treatments, however simple or complex, are about discussing options and shared decision making with their patients. As doctors we have a responsibility to our patients to provide them with treatment options that have the best levels of evidence to prove their efficacy. In the cosmetic industry this, unfortunately, is not always the case.
At Rejuvence we are passionate about offering our clients evidence based treatments that have been shown to work. Where the evidence base is not very strong we are quick to point this out. We are the experts in anti-ageing and aesthetic medicine but we also acknowledge you are the experts of your face.
Collagen provides the skin with its tensile strength and is dependent upon a criss-cross structure in the dermis (deep layer) of the skin. As we age the amount of collagen reduces and it loses this arrangement. As a result skin is thinner and loses its strength. Excessive sun exposure, smoking and high caffeine consumption can worsen this process.
Elastin forms a unique relationship with collagen and provides the skin with its elastic properties. With age the amount of elastin reduces and its interaction with collagen is compromised. Skin becomes lax and loose. It tends to sag. Excessive sun exposure and smoking can worsen this process significantly.
Hyaluronic acid is found in large quantities in healthy skin. It is responsible for carrying large numbers of water molecules and provide skin with hydration and gives it a plump and soft feel. With ageing levels of hyaluronic acid reduce and skin can dry out and become sallow and dull. As is the case with collagen and elastin, the process of ageing and reduction of hyaluronic acid is significantly worsened by excessive sun exposure and smoking.
Treatment specifically targeted at the skin includes topical skincare products including serums and creams that help to increase fibroblast activity. Fibroblasts are responsible for collagen and elastin production. Retinol and tretinoin are the best studied products and have been shown to increase collagen and elastin levels. Chemical peels can be used to improve skin texture following adequate skin preparation. Specific collagen induction therapies including micro needling result in increased collagen levels. Platelet rich plasma with micro needling can have a dramatic effect on increasing fibroblast activity and can return a glow to aged skin. This can last up to 18 months. Ultimately the effects of these treatments will be short lived if specific lifestyle changes are not made including reduced sun exposure and smoking cessation. Healthy skin function can be maintained irrespective of age as long as a good skincare program is used.
Regions of volume loss can be addressed using dermal fillers. Injections of hyaluronic acid into the deep fat compartment can go a long way to restoring a youthful appearance. The ultimate natural filler is, of course, your own fat and fat transfer provides the best long term solution to volume loss.
Where there is excessive volume in the superficial fat parcels and together with weakening of ligaments, there is a general sagging of the face. Gravity also plays a significant role over time. In this case a lifting effect is required. This can be achieved with appropriate placement of dermal fillers or fat, to emphasise cheek regions. Sagging jawline can be hidden with clever placement of hyaluronic acid dermal fillers. A direct lifting effect can be provided by the use of threads such as PDO or PCL threads that can be used to lift the jawline and cheek as well as tighten the neck.
With ageing there are changes to the muscles of the face. Most notably with the increased use of facial muscles with age they hypertrophy (increase in size and become stronger). As a result they can over stretch the skin and deeper structures. Alongside increased laxity and thinning of the skin with age, there are increases in wrinkling especially around the forehead and the corner of the eyes (crow’s feet). The down turn of lip corners (marionette lines) and cords in the neck can also form as a result of muscle hypertrophy (increase in size and strength).
The use of wrinkle relaxing injections is amongst the oldest aesthetic techniques. Injection of botulinum toxin type A into regions of the forehead and corners of the eyes as well as around the bridge of the nose can help in the reduction of dynamic facial lines. Dynamic lines are lines that are only seen on moving certain parts of the face in frowning, smiling and in raising the eyebrows. Static lines describe wrinkles and fine lines that are always present irrespective of facial movements. These are only partially treated with wrinkle relaxing injections.
